Of Italy’s 20 regions, Sicily is the most southerly, and is also the largest island in the Mediterranean Sea. Sicily's climate is Mediterranean, characterized by mild winters and hot, dry summers. Most of its winemaking takes place along the coast; to the north west, there are the regions of Trapani and Palermo, and to the east, there are the volcanic regions of Catania and Etna. The island’s most well-known red grape varieties are Nero d’Avola, Frappato and Nerello Mascalese. Their most well known whites are Catarratto, Caricante, Grillo, Grecanico and Inzola.